What is NAD?

Learn how NAD+ can extend your healthspan.

USC Study: Longevity-Promoting Drug Counteracts a Genetic Predisposition to Alzheimer's

Seragon’s Aging Intervention Drug SRN-901 Achieves One of the Largest Extensions of Lifespan and Healthspan to Date

Spermidine: A Promising Nutrient for Brain Health and Cognitive Aging

Anti-Aging Drug Rapamycin Extends Life as Much as Dieting, New Study Shows

New Study: Diabetes Medication Improves Cognition and Alleviates Alzheimer’s Progression

The UN’s Brief on the Biology of Aging

Fisetin Fights Frailty: New Study Shows Supplment Preserves Strength

NMN & NR

Nicotinamide mononucleotide (NMN) increases blood levels of nicotinamide adenine dinucleotide (NAD+) to alleviate age-related disorders like metabolic disease and cardiovascular dysfunction.

Clinical Trials

New Study Shows NMN Substantially Increases NAD+ and Enhances Physical Performance

NMN increases blood NAD+, enhances walking distance over a six-minute period, and improves a self-assessed evaluation of health, especially at higher doses in healthy adults.

Harvard Study: NMN Cuts Weight, Cholesterol, and Blood Pressure in Overweight Adults

NMN supplementation significantly reduces body weight, cholesterol, and blood pressure when blood fills the heart (diastolic blood pressure) in overweight or obese adults.

Latest UPenn Study Reveals NMN and NR Have Similar Efficacy in a Kidney Disease Model

Supplementing with nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR) confers comparable benefits against kidney disease in male mice.

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

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Aging & Longevity

David Sinclair’s 2024 Anti-Aging Supplement Protocol

Longevity expert Dr. David Sinclair's 2024 anti-aging protocol includes NMN, fish oil, lipoic acid, resveratrol, metformin, spermidine, and more.

Aging & Longevity

94-Year-Old Clint Eastwood’s Longevity Secrets

A series of realizations and personal experiences — like his father’s death from cardiovascular disease — have propelled Clint Eastwood to take care of his health for graceful aging.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

The potential pitfalls of boosting NAD+ levels with NR, NMN, niacin, and nicotinamide are discussed.

The potential pitfalls of boosting NAD+ levels with NR, NMN, niacin, and nicotinamide are discussed.

Aging & Longevity

How 84-Year-Old Acting Legend Chuck Norris Defies Aging

Chuck Norris eats whole, nutrient-dense foods, maintains a rigorous workout routine that includes martial arts training, and practices meditation to stay young.

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Latest News

Aging & Longevity

Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

A new human study shows that a procedure involving the replacement of blood plasma with a fresh solution (therapeutic plasma exchange) lowers a measure of how quickly the body is aging (biological age).

Cornell and UPenn scientists find that mice introduced to the wild as infants age faster than lab mice, but what does this mean for humans?

Cornell and UPenn scientists find that mice introduced to the wild as infants age faster than lab mice, but what does this mean for humans?

Aging & Longevity

German researchers discover rare genetic mutations related to the mTOR pathway in the DNA of long-lived individuals.

German researchers discover rare genetic mutations related to the mTOR pathway in the DNA of long-lived individuals.

Brain & Neurons

New Study Suggests NR Modestly Improves Cognition in Age-Related Vascular Disease

Taking NR was associated with improved blood flow to a specific brain region following cognitive stimulation, as well as trends toward enhanced cognition in patients with age-related vascular disease.

Aging & Longevity

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Brain & Neurons

Supplementing with 20 grams of creatine improves the cognition of individuals with Alzheimer’s disease.

Supplementing with 20 grams of creatine improves the cognition of individuals with Alzheimer’s disease.

Brain & Neurons

Restoring the essential molecule NAD+ may potentially hold the key to treating Alzheimer’s, as Harvard researchers emphasize the role of low brain NAD+ in this devastating disease.

Restoring the essential molecule NAD+ may potentially hold the key to treating Alzheimer’s, as Harvard researchers emphasize the role of low brain NAD+ in this devastating disease.

University of California, Irvine (UCI) scientists identify a NAD+ precursor in mice that declines with age and mitigates age-related kidney decline.

University of California, Irvine (UCI) scientists identify a NAD+ precursor in mice that declines with age and mitigates age-related kidney decline.

Aging & Longevity

Ranked fourth on the Rejuvenation Olympics leaderboard, 30-year-old Siim Land lists the supplements he takes to stay young.

Ranked fourth on the Rejuvenation Olympics leaderboard, 30-year-old Siim Land lists the supplements he takes to stay young.

Brain & Neurons

New Study Finds Midlife May Be a Critical Window to Prevent Brain Aging

A new study suggests that supplementing with ketones—molecules the body can use for energy when lacking sugars—prevents cognitive aging when administered in people’s 40s and 50s.

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