What is NAD?

Learn how NAD+ can extend your healthspan.

Harvard Study: A Low Dose of Lithium May Preserve Cognitive Resilience with Age

Seragon’s Aging Intervention Drug SRN-901 Achieves One of the Largest Extensions of Lifespan and Healthspan to Date

New Oxford Study: Powerful Longevity Drug Rapamycin Targets Cell Senescence

Scientist May Have Discovered a New Drug that Makes Up for Lost Sleep

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

Enlivien: A New Dawn for Sleep and Longevity

Top Aging Expert & Peter Attia Discuss NAD+ Precursors: Taking NMN and NR Together

NMN & NR

Nicotinamide mononucleotide (NMN) increases blood levels of nicotinamide adenine dinucleotide (NAD+) to alleviate age-related disorders like metabolic disease and cardiovascular dysfunction.

Clinical Trials

New Study Shows NMN Substantially Increases NAD+ and Enhances Physical Performance

NMN increases blood NAD+, enhances walking distance over a six-minute period, and improves a self-assessed evaluation of health, especially at higher doses in healthy adults.

Harvard Study: NMN Cuts Weight, Cholesterol, and Blood Pressure in Overweight Adults

NMN supplementation significantly reduces body weight, cholesterol, and blood pressure when blood fills the heart (diastolic blood pressure) in overweight or obese adults.

Latest UPenn Study Reveals NMN and NR Have Similar Efficacy in a Kidney Disease Model

Supplementing with nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR) confers comparable benefits against kidney disease in male mice.

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

Most Popular

Aging & Longevity

David Sinclair’s 2024 Anti-Aging Supplement Protocol

Longevity expert Dr. David Sinclair's 2024 anti-aging protocol includes NMN, fish oil, lipoic acid, resveratrol, metformin, spermidine, and more.

Aging & Longevity

94-Year-Old Clint Eastwood’s Longevity Secrets

A series of realizations and personal experiences — like his father’s death from cardiovascular disease — have propelled Clint Eastwood to take care of his health for graceful aging.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults.

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults.

The potential pitfalls of boosting NAD+ levels with NR, NMN, niacin, and nicotinamide are discussed.

The potential pitfalls of boosting NAD+ levels with NR, NMN, niacin, and nicotinamide are discussed.

Now Welcoming Guest Post Submissions!

Contact Us arrow-down

Latest News

Aging & Longevity

Anti-Aging Breakthrough? Harvard's David Sinclair Predicts Age-Reversing Pill by 2035

A leading thinker in the field of aging research, Dr. David Sinclair, shares insights on the rapid pace of advancements in aging research and predicts the availability of age-reversing pills within the next 10 years.

While improving immune health, the NAD+ (nicotinamide adenine dinucleotide) precursor NR (nicotinamide riboside) may induce anxiety-like behavior in stressed, aged mice.

While improving immune health, the NAD+ (nicotinamide adenine dinucleotide) precursor NR (nicotinamide riboside) may induce anxiety-like behavior in stressed, aged mice.

Aging & Longevity

Supplements like NAD+ boosters may benefit older individuals, while drugs like metformin and interventions such as physical exercise may not, according to German scientists.

Supplements like NAD+ boosters may benefit older individuals, while drugs like metformin and interventions such as physical exercise may not, according to German scientists.

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults.

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults.

Clinical Trials

A natural supplement, quercetin, targets age-promoting senescent cells, reduces inflammation, and counteracts blood vessel aging in men with heart disease.

A natural supplement, quercetin, targets age-promoting senescent cells, reduces inflammation, and counteracts blood vessel aging in men with heart disease.

Aging & Longevity

New Study: Combining NR with NAC May Slow Telomere Shortening

New research suggests that nicotinamide riboside (NR) combined with N-acetyl cysteine (NAC) prevents telomere shortening linked to genetic sequences within the cell’s powerhouse (mitochondria) in human cells.

Clinical Trials

An extract made from Monarda didyma L. reduces the biological age of older adults while improving their quality of life.

An extract made from Monarda didyma L. reduces the biological age of older adults while improving their quality of life.

A vaccine targeting an enzyme that breaks down NAD+, called CD38, counteracts signs of aging in mice.

A vaccine targeting an enzyme that breaks down NAD+, called CD38, counteracts signs of aging in mice.

Brain & Neurons

USC Study: Longevity-Promoting Drug Counteracts a Genetic Predisposition to Alzheimer's

The drug alfatradiol, also known as 17ɑ-estradiol, reduces cognitive errors on a test of memory and lowers neuronal plaques in mice genetically predisposed to Alzheimer’s disease.

Brain & Neurons

Human studies show that a higher intake of the naturally occurring molecule spermidine may prevent cognitive impairments and dementia while improving longevity.

Human studies show that a higher intake of the naturally occurring molecule spermidine may prevent cognitive impairments and dementia while improving longevity.

SHOW MORE