Model: Male Sprague Dawley rats
Dosage: 1.5 mg/kg body or rapamycin injected 3 times a week for 4 weeks

The longevity-associated drug rapamycin diminishes muscle size and strength in young rats when compared to untreated but calorically restricted young rats. 

Skin &amp; Muscle

Globally, 9.8% of Diabetes Cases Attributable to Sugary Drinks

A worldwide assessment suggests that 9.8% of new diabetes cases and 3.1% of new cardiovascular disease cases are attributable to sugar-sweetened beverage consumption.

(The study’s principal investigator, Dr. Dariush Mozafarrian | ResearchGate)

Metabolism

Transplanting a population of “young” stem cells from old mice prolongs the lifespan of middle-aged mice and delays manifestations of aging. 

Aging &amp; Longevity

Columbia University scientists find that senolytics — compounds that remove age-promoting cells — restore hair follicle regeneration in a human cell/mouse model. 

Cumulative Research Suggests Coffee Prolongs Life by 1.8 Years

Worldwide, people consume about 2 billion cups of coffee a day, and a new review associates drinking this caffeinated beverage regularly with an average of 1.8 years added to lifespan.

Model: 3-month-old LDLR−/− pigs
Dosage: 400 nM of SWNT or SWNT-SHP1i 
was infused intravenously for ~15–30 min, once a week, for 12 weeks

“Trojan Horse” Nanoparticles: A Breakthrough in Treatment for Atherosclerosis 

Stanford School of Medicine researchers develop safe nanoparticles that target dying cells in atherosclerotic plaque and reduce vascular inflammation.

Cardiovascular

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging

The longevity biotech company, MetaShape, has a new compound designed to restore cellular nicotinamide adenine dinucleotide (NAD+) and offset elevated cholesterol, cognitive decline, and neurodegeneration.

Supplementing with ergothioneine — a compound found in lion’s mane mushrooms — enhances the verbal memory of elderly individuals. 

(Image: marthastewart.com) Lion’s mane mushrooms.

Betaine Supplement Prevents Age-Related Loss of Muscle Size and Strength

Betaine prevents loss of muscle mass and strength while enhancing autophagy in old mice.

New Study Shows How Boosting NAD+ Could Protect Against Parkinson’s

Recent research from Zhejiang University School of Medicine in Hangzhou, China, demonstrates that administering NAD+ precursors to mice can safeguard the brain against neurodegeneration

(Zhejiang University School of Medicine | Panda Admission)

Over-Supplementing in Youth Can Harm Long-Term Health, Says New Research

Globally, 9.8% of Diabetes Cases Attributable to Sugary Drinks

“Young” Stem Cells Hidden in Our Body Can Increase Our Length of Life, New Research Suggest

Can Senolytic Supplements Restore Hair Growth? What the New Research Says

Cumulative Research Suggests Coffee Prolongs Life by 1.8 Years

“Trojan Horse” Nanoparticles: A Breakthrough in Treatment for Atherosclerosis

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging

Ergothioneine Longevity Supplement Enhances Verbal Memory

Betaine Supplement Prevents Age-Related Loss of Muscle Size and Strength

New Study Shows How Boosting NAD+ Could Protect Against Parkinson’s