What is NAD?

Learn how NAD+ can extend your healthspan.

16-Hour Intermittent Fasting Improves Health and Longevity, New Study Confirms

Seragon Publishes Record-Breaking SRN-901 Longevity Data, Demonstrating 33% Lifespan Extension in Mice

New Framework Uncovers 21 Existing Drugs with Pro-Longevity Potential

Powerful Antioxidant PQQ Extends Life and Improves Strength, New Study Shows

Examining Evidence for the Cognition-Enhancing Potential of the Antioxidant Astaxanthin

Dasatinib and Quercetin Delay Early-Onset Disc Degeneration in Mice

Yeast Supplement Improves Cognitive Function in Older Adults with Mild Cognitive Impairment

NMN & NR

Nicotinamide mononucleotide (NMN) increases blood levels of nicotinamide adenine dinucleotide (NAD+) to alleviate age-related disorders like metabolic disease and cardiovascular dysfunction.

Clinical Trials

New Study Shows NMN Substantially Increases NAD+ and Enhances Physical Performance

NMN increases blood NAD+, enhances walking distance over a six-minute period, and improves a self-assessed evaluation of health, especially at higher doses in healthy adults.

Harvard Study: NMN Cuts Weight, Cholesterol, and Blood Pressure in Overweight Adults

NMN supplementation significantly reduces body weight, cholesterol, and blood pressure when blood fills the heart (diastolic blood pressure) in overweight or obese adults.

Latest UPenn Study Reveals NMN and NR Have Similar Efficacy in a Kidney Disease Model

Supplementing with nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR) confers comparable benefits against kidney disease in male mice.

NMN Protects the Heart from Chemotherapy Toxicity

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

Most Popular

High-Dose Supplement Shrinks Arterial Plaque by 36%

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

Aging & Longevity

Aging Guru Bryan Johnson’s Supplement List for 2026

Changes to Bryan Johnson’s latest supplement stack include taking NMN or NR six days a week, rather than seven, and eliminating the use of rapamycin.

Aging & Longevity

Joe Rogan’s Top Supplements for 2026

Joe Rogan’s latest supplement stack includes compounds targeting longevity, cognition, immunity, fitness, and optimal hormone levels.

Aging & Longevity

Andrew Huberman’s Updated Supplement Stack for 2026

Stanford neuroscientist Andrew Huberman’s updated supplement list includes the NAD+ precursor NMN, along with other compounds for sleep and cognitive performance.

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Latest News

Aging & Longevity

Restoring the naturally occurring antioxidant, alpha-lipoic acid (ALA), to the gut wall rejuvenates stem cells and counters age-related gut degeneration in mice and human models.

Restoring the naturally occurring antioxidant, alpha-lipoic acid (ALA), to the gut wall rejuvenates stem cells and counters age-related gut degeneration in mice and human models.

Aging & Longevity

Russia’s $27 Billion Bet on Beating Aging—Hype or Hope?

With an ambitious goal of conquering aging, Russia is investing $26 to $28 billion in a national health initiative.

Aging & Longevity

Top Evidence-Based Interventions to Lower Biological Age

Epigenetic aging clocks estimate biological age based on DNA molecular tagging patterns, and interventions like semaglutide and ketamine reduce these estimates in humans.

Oxford scientists find that spermidine, a naturally occurring molecule that declines with age, rejuvenates aging immune cells and improves vaccine protection in older adults.

Oxford scientists find that spermidine, a naturally occurring molecule that declines with age, rejuvenates aging immune cells and improves vaccine protection in older adults.

Japanese scientists have found that reducing NAD+ (nicotinamide adenine dinucleotide) transport into mitochondria within the fat tissue of mice induces metabolic dysregulation and obesity.

Japanese scientists have found that reducing NAD+ (nicotinamide adenine dinucleotide) transport into mitochondria within the fat tissue of mice induces metabolic dysregulation and obesity.

Brain & Neurons

Duke University scientists have successfully induced new neuronal connections in the brains of mice, leading to improvements in social interaction and stress resilience.

Duke University scientists have successfully induced new neuronal connections in the brains of mice, leading to improvements in social interaction and stress resilience.

Aging & Longevity

Losartan, a common blood pressure medication, increases the survival rate of mice and improves the metabolic outlook of pre-frail older adults.

Losartan, a common blood pressure medication, increases the survival rate of mice and improves the metabolic outlook of pre-frail older adults.

Aging & Longevity

New Study: Transferring Gut Microbes from Old to Adult Mice Shortens Lifespan

Spanish scientists unveil data showing that transferring fecal microbes from old to adult mice increases biological age and shortens lifespan.

Anthocyanin, a compound found in berries, reduces inflammation and heart disease markers in older adults at risk for dementia.

Anthocyanin, a compound found in berries, reduces inflammation and heart disease markers in older adults at risk for dementia.

Aging & Longevity

David Attenborough Turns 100: 5 Longevity Habits of the Renowned British Broadcaster

David Attenborough’s longevity secrets encompass simple practices, such as walking, eating plant foods, spending time in nature, and maintaining social connections.

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