What is NAD?

Learn how NAD+ can extend your healthspan.

Why Low Testosterone Isn’t Just About Getting Older: New U.S. Army Findings Point to Belly Fat

Seragon Publishes Record-Breaking SRN-901 Longevity Data, Demonstrating 33% Lifespan Extension in Mice

NMN Enhances Stem Cell Therapy’s Effects on Immune Aging in Latest Study

New Study: Gut Bacteria Metabolite Reduces Arterial Plaque Burden by 50%

Does Fasting Really Trigger Autophagy? New Study Challenges Popular Longevity Belief

Protein Restriction and Longevity: Can Limiting Protein Intake Support Healthy Aging?

New Mayo Clinic Study: Forcibly Depleting NAD+ Shortens Lifespan

NMN & NR

Nicotinamide mononucleotide (NMN) increases blood levels of nicotinamide adenine dinucleotide (NAD+) to alleviate age-related disorders like metabolic disease and cardiovascular dysfunction.

New Study Shows NMN Substantially Increases NAD+ and Enhances Physical Performance

NMN increases blood NAD+, enhances walking distance over a six-minute period, and improves a self-assessed evaluation of health, especially at higher doses in healthy adults.

Harvard Study: NMN Cuts Weight, Cholesterol, and Blood Pressure in Overweight Adults

NMN supplementation significantly reduces body weight, cholesterol, and blood pressure when blood fills the heart (diastolic blood pressure) in overweight or obese adults.

Latest UPenn Study Reveals NMN and NR Have Similar Efficacy in a Kidney Disease Model

Supplementing with nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR) confers comparable benefits against kidney disease in male mice.

NMN Protects the Heart from Chemotherapy Toxicity

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

Most Popular

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

High-Dose Supplement Shrinks Arterial Plaque by 36%

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults.

Aging & Longevity

Joe Rogan’s Top Supplements for 2026

Joe Rogan’s latest supplement stack includes compounds targeting longevity, cognition, immunity, fitness, and optimal hormone levels.

Aging & Longevity

Andrew Huberman’s Updated Supplement Stack for 2026

Stanford neuroscientist Andrew Huberman’s updated supplement list includes the NAD+ precursor NMN, along with other compounds for sleep and cognitive performance.

People with Higher Cholesterol Live Longer than People with Lower Cholesterol

Older adults with LDL cholesterol levels above 130 mg/dL live longer than older adults with LDL cholesterol levels below 130 mg/dL.

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Latest News

Aging & Longevity

The Harvard geneticist discussed an early human trial, unpublished mouse results, and an AI-assisted search for chemical rejuvenation therapies on the Joe Rogan Experience.

The Harvard geneticist discussed an early human trial, unpublished mouse results, and an AI-assisted search for chemical rejuvenation therapies on the Joe Rogan Experience.

Aging & Longevity

Aging Clocks Applied to Human Trial Data Support AI-Designed Drug Lowering Age

Six proteomics-based aging clocks (age assessments from large-scale analyses of proteins) agreed that patients treated with the AI-designed drug rentosertib appeared younger.

Diabetes & Obesity

Supplementing chronically stressed mice with L-serine, an amino acid, counters signs of anxiety and diabetes while diverting age-promoting senescent cells within the brain’s fear center.

Supplementing chronically stressed mice with L-serine, an amino acid, counters signs of anxiety and diabetes while diverting age-promoting senescent cells within the brain’s fear center.

Aging & Longevity

Can Testing Drugs in Five Species Help Us Find Treatments for Healthy Aging?

A new study describes a large cross-species testing system—using species from yeast to mice—to identify promising lifespan-extending drug candidates more efficiently.

Aging & Longevity

Semaglutide extends mouse lifespan and targets signs of aging, such as diminished NAD+, while mimicking the anti-aging effects of caloric restriction (consuming fewer calories).

Semaglutide extends mouse lifespan and targets signs of aging, such as diminished NAD+, while mimicking the anti-aging effects of caloric restriction (consuming fewer calories).

Aging & Longevity

New Study Supports Repurposing Glucosamine Against Liver Aging

A sugar-like compound found in cartilage called glucosamine reduces dysfunctional cells (senescent cells) in the liver and attenuates liver damage from alcohol consumption in mice.

Scientists find that meloxicam preserves muscle mass and strength in aged mice while sustaining mitochondrial function and activating multiple molecules associated with longevity.

Scientists find that meloxicam preserves muscle mass and strength in aged mice while sustaining mitochondrial function and activating multiple molecules associated with longevity.

Researchers found that a compound found in garlic supports healthier muscle aging by boosting cellular defenses linked to longevity and maintaining physical performance.

Researchers found that a compound found in garlic supports healthier muscle aging by boosting cellular defenses linked to longevity and maintaining physical performance.

Brain & Neurons

Study shows that urolithin A preserves memory and cognitive function during aging when treatment begins before age-related decline, but does not reverse cognitive impairment once it is established.

Study shows that urolithin A preserves memory and cognitive function during aging when treatment begins before age-related decline, but does not reverse cognitive impairment once it is established.

Aging & Longevity

Repurposing Erectile Dysfunction Pills for Longevity

Some people are taking erectile dysfunction medications like Cialis and Viagra for more than sex—rather, to help them live longer.

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