Model: 40 aged patients with COPD with an average age of 71.9 
Dosage: One gram of NR taken twice daily for a total of two grams per day for six weeks

Fresh Insights: NR’s Effects on Inflammation in Age-Related Lung Disease

Taking nicotinamide riboside (NR) is tied to a 52.6% reduction of an inflammatory protein in the sputum—mucus coughed up from the respiratory tract—of patients with chronic obstructive pulmonary disease (COPD).

(Principal investigator Dr. Morten Scheibye-Knudsen, Associate Professor from the University of Copenhagen | Videnskab DK)

NR (nicotinamide riboside) improves the walking performance of individuals with cardiovascular disease, but adding resveratrol does not improve performance further. 



Nicotinamide riboside improves the physical performance of cardiovascular diseases patients. 

NAD+ Precursors, Aging, and Longevity: Dr. Peter Attia’s Thoughts

Dr. Peter Attia shares his thoughts on NAD+ precursors, their potential impact on aging and longevity, and the importance of further research in this field.

Aging &amp; Longevity

Model: C57BL/6J mice and Abca1/g1-m/-m mice of both sexes and bone marrow-derived macrophages from C57BL/6J and Abca1/g1-m/-m mice
Dosage: 300 mg/kg of NMN by daily intraperitoneal injection for two weeks, 5 mg/kg of dasatinib and 50 mg/kg of quercetin by oral gavage for five consecutive days every two weeks for three months, and a 500 μM concentration of NMN for bone marrow-derived macrophages in laboratory dishes

Revitalizing Immune Cells & Eye Function: NMN Study Unveils Remarkable Findings

A new study suggests that NMN reverses an age-associated dysfunctional cellular state — senescence — in immune cells and restores eye function in an age-related eye disease mouse model.

(An anatomical view of an eye with age-related macular degeneration | NAD.com)

NMN reverses an age-related dysfunctional state in immune cells — senescence — and improves eye function in an age-related eye disease mouse model.

Based primarily on discussions with guests on his popular podcast, the supplements Joe Rogan has taken include NMN, resveratrol, vitamin D, fish oil, and more.  



Joe Rogan (Image: Joe Rogan’s X account) 

The supplements that Joe Rogan has taken, according various social media posts and conversations he's had with guest on his podcast. 

65-year-old Dr. Drew Pinsky, who has been taking NR for about 10 years, said, “If I had access to only one supplement, NR would be that supplement.” 

Dr. Drew says if he could take only one supplment, it would be NR. 

David Sinclair’s 2024 Anti-Aging Supplement Protocol

Longevity expert Dr. David Sinclair's 2024 anti-aging protocol includes NMN, fish oil, lipoic acid, resveratrol, metformin, spermidine, and more.

Scientists maintain the function of fat-derived stem cells by boosting NAD+ with nicotinamide riboside (NR), which could combat age-related liver and muscle ailments.



A woman next to a nicotinamide riboside (NR) molecule. 

Model: Male C57BL/6 mice
Dosage: 400 mg/kg/day by oral gavage for 21 days starting at eight weeks after ionizing radiation exposure

NAD+ Precursor NR Reduces Side Effects of Anticancer Radiation Therapy: New Study

Researchers show nicotinamide riboside (NR) restores exercise capacity, increases white and red blood cells, and alleviates stem cell senescence in prematurely aged mice exposed to radiation for treating cancer.

(An aged mouse undergoing ionizing radiation cancer therapy | NAD.com)

NR restores physical function, increases blood cell counts, and reduces bone marrow stem cell senescence in mice exposed to ionizing radiation.

NAD Precursor NR Reduces Side Effects of Anticancer Radiation Therapy, Reveals New Study

Model: Adults between 55 and 70 years of age for measuring how different NMN dosages affect blood NAD+ concentrations
Dosage: 500 mg or 1,000 mg per day of oral NMN for 30 days

New NAD+ Blood Test Kit Available

Researchers unveil an easy-to-use and cost-effective blood nicotinamide adenine dinucleotide (NAD+) concentration reading device that they apply to confirm falling NAD+ in aged humans and NMN's restorative effects on NAD+ levels.

(Pricking one’s finger to collect a blood sample for an NAD+ concentration reading)

Discover the groundbreaking finger-prick blood test that confirms the decline of NAD+ levels in aging humans. Explore the latest insights and findings at NAD.com to understand the science behind aging and NAD+ decline.

Fresh Insights: NR’s Effects on Inflammation in Age-Related Lung Disease

NAD+ Precursor NR Improves Physical Performance but not Resveratrol: New Clinical Study

NAD+ Precursors, Aging, and Longevity: Dr. Peter Attia’s Thoughts

Revitalizing Immune Cells & Eye Function: NMN Study Unveils Remarkable Findings

Podcaster Joe Rogan’s Top 2024 Supplements Beyond NAD+ Precursor NMN

Dr. Drew Says NR is the Best NAD+ Precursor

David Sinclair’s 2024 Anti-Aging Supplement Protocol

When More Fat is Good: Study Shows NAD⁺ Precursor NR Rejuvenates Fat Stem Cells

NAD⁺ Precursor NR Reduces Side Effects of Anticancer Radiation Therapy: New Study

New NAD⁺ Blood Test Kit Available