Model: Humans aged 40 to 65 years
Dosage: 300 mg, 600 mg, or 900 mg of NMN per day for 60 days

New Study Shows NMN Substantially Increases NAD+ and Enhances Physical Performance

NMN increases blood NAD+, enhances walking distance over a six-minute period, and improves a self-assessed evaluation of health, especially at higher doses in healthy adults.

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NMN triggers higher blood NAD+ levels, along with improved muscle function and overall health and wellbeing.

Model: Adults with non-alcoholic fatty liver disease
Dosage: 250 mg nicotinamide riboside and 50 mg pterostilbene per day or 500 mg nicotinamide riboside and 100 mg pterostilbene per day

NAD+ Booster Combo Reduces Inflammation in Liver Disease

MIT professor Leonard Guarente leads a study showing nicotinamide riboside (NR) and pterostilbene reduce inflammatory markers in adults with non-alcoholic fatty liver disease (NAFLD).

guarente

Leonard Guarente PhD

(Senior author and founder of Elysium Health Leonard Guarente, PhD | Ageist)

A NR and pterostilbene combination supplement reduces the abundance of blood markers for liver inflammation and a toxic fat that contributes to liver disease.

Clinical Trials

Model: female E4FAD mice 
Diet: Day 1 = 55% fat, 36% carbohydrate, and 9% protein. Day 2-5 = 43.3% fat, 47.4% carbohydrate, and 9.3% protein.

Fasting-Mimicking Diet Reduces Alzheimer’s Pathology

Feeding Alzheimer’s model mice a diet low in protein but high in fats reduces brain inflammation, restores new neuron production, and improves cognition. 


volter

Volter

Senior author, Dr. Volter D. Longo | USC Pressroom 

Model: Human older adult
Dosage: 1000 mL of plasma each week for 10 weeks

Young Blood Improves Kidney Function and Reverses Biological Age

Older adults receiving plasma from umbilical cord blood exhibit improved kidney function and decreased morbidity and mortality risk based on age-related DNA changes.


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Doctor,In,Blue,Gloves,Keep,In,Hands,Test,Tube,With

Tube of plasma (yellow) separated from blood | Lilja Malanjak (shutterstock.com)

Old Adults: (70-80 years old) ; Young Adults: (20-30 years old)
GlyNAC: capsules containing glycine (1.33 mmol/kg/day) and N-acetylcysteine (0.81 mmol/kg/day) once a week for 24 weeks

Signs of Aging Significantly Reversed with Antioxidant Cocktail 

Clinical trial results show that glycine and N-acetylcysteine (GlyNAC) improves cognition, boosts physical performance, and mitigates insulin resistance in older adults. 


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KUMAR3

Corresponding author, Dr. Rajagopal V. Sekhar | Baylor College of Medicine 

New Human Study Shows NMN Substantially Increases NAD+ and Enhances Physical Performance

Elysium Scientists Combine NAD+ Booster with Sirtuin Activator to Reduce Inflammation in Liver Disease

USC Scientists Reveal that Fasting-Mimicking Diet Reduces Brain Pathology and Cognitive Decline in Alzheimer’s

UCLA Scientists Show Young Blood Improves Kidney Function and Reverses Biological Age

Baylor College Scientists Reverse Signs of Aging with Antioxidant Cocktail in Older Adults