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Is NAD⁺ Joe Rogan’s Secret to Long-Form Conversation?

The most successful podcast of all time may be powered by NAD+

By Griffin Dean

Key Points: 

  • Business executive and blogger Lulu Cheng Meservey gives a behind the scenes look of Joe Rogan’s podcast. 
  • She explains that Rogan takes an NAD+ shot just before recording a podcast episode. 

Joe Rogan is a comedian and UFC commentator best known for his podcast the Joe Rogan Experience on Spotify. Astonishingly, Rogan and his guests hold the attention of an estimated 11 million listeners per episode. Even more perplexing in an online world of 15-second videos is that each podcast last an average of 2 hours and 37 minutes. So, what makes these long-form conversations so interesting?

Lulu Cheng Meservey, now an executive at Activision Blizzard describes her experience with the Joe Rogan podcast on her personal blog Flack. As the Substack Vice President of Communications at the time, she joined Substack CEO Chris Best, a guest on the Joe Rogan Experience in early August of 2022. Among her discoveries, she found that Joe and his guests partake in some NAD+ before the show. 

Behind the Scenes of the Joe Rogan Experience 

In her blog, Meservey explains her trip to Joe’s recording studio in Austin, Texas. She details the booking process and mentions that Joe mostly books his own guests via text or email. Joe only chooses folks he thinks are fun or interesting and doesn’t choose guests for the downloads, which is why he denied a podcast with Donald Trump. 

The “Buckingham Palace of Man Caves” 

Upon entering the studio, Meservey notes that the place isn’t too far off from Hansel’s loft in Zoolander. The walls are covered with imagery, including mugshots of legendary figures such as Rosa Parks, Jim Morrison, and Jimi Hendrix. The décor also includes Samurai armor and a werewolf. Joe notes: The wolf is from an American Werewolf in London, not Paris. The Paris movie sucked!

Continuing through the large building, Meservey sees that the studio contains most of what is necessary for Joe’s hobbies. There is a large pool room, a huge gym with fighting gear, and an indoor archery range. Of course, the archery range is equipped with a Kevlar screen that can be shot at with real arrows. 

 Inside Joe Rogan's Man Cave. Top left: Collage of mugshots featuring Rosa Parks, Mick Jagger, Jim Morrison, Jimi Hendrix, and David Bowie. Top right: Display of Samurai armor and a mugshot of Pablo Escobar. Bottom left: Artwork depicting an American werewolf. Bottom right: Fitness gym area.
Joe Rogan’s Man Cave. Top left: mugshots of Rosa Parks, Mick Jagger, Jim Morrison, Jimi Hendrix, and David Bowie. Top right: Samurai armor and mugshot of Pablo Escobar. Bottom left: American werewolf. Bottom right: gym.

Would you Like a Shot of NAD+?

Meservey goes on to describe the main room of the studio where an attractive nurse offers her, Chris Best, and the rest of the entourage some B12 or NAD+, via shot or intravenously. She chooses the shot and writes: 

“Actually, I don’t know what any of it is, but the nurse said she takes it, and if you saw this woman, you too would ask for a shot of whatever she’s on.” 

The communications executive then writes that just before taping the show, Joe took his own jab of NAD+. She writes: 

“His might be NAD+++ though, judging by the resulting energy levels, because he then proceeds to power through several hours of podcasting followed shortly afterwards by a standup show at a local bar.”

What’s the Secret to Joe’s Podcast Success?

Most would say it’s his authenticity. Rogan himself has said that the success of his podcast could be attributed to his willingness to speak openly. Unlike interviewers on corporate television and radio, Rogan doesn’t have to worry about the influence of managers, television producers, television executives, or corporate advertisers. 

Still, how does Joe have the energy to record 3 to 4 podcasts per week? Other than choosing guests that he is genuinely interested in, a jab of NAD+ just before a show couldn’t hurt. 

NAD+ plays an essential role in capturing the energy stored within the chemical bonds of proteins, fats, and carbohydrates from the food we eat. NAD+ carries this energy (in the form of electrons) to and within mitochondria, which produce cellular energy (in the form of ATP). This is how boosting NAD+ can increase cellular energy, including brain cell energy. In this way, NAD+ could enhance brain function, including cognitive function, allowing for sustained conversation. 

 NAD+ Role in Cellular Energy Generation. NAD+ captures electrons to form NADH, which transports electrons to the mitochondria's electron transport chain. This process facilitates the production of cellular energy in the form of ATP.
NAD+ Promotes the Generation of Cellular Energy. NAD+ captures energy in the form of electrons and becomes NADH. The electrons are then carried to the electron transport chain in mitochondria where they are utilized to produce energy in the form of ATP.

What are NAD+ Shots?

NAD+ shots are needle and syringe-injections of NAD+ that enter directly into the bloodstream. Unlike intravenous NAD+ therapy, which slowly infuses into the bloodstream, shots are a one-time quick injection per dose. Such shots can be purchased online and do not require going to a clinic like with intravenous therapy. However, the risks involved with self-administered NAD+ injections are the same as with any self-administered injections.   

Another less invasive option than either NAD+ shots or intravenous NAD+ is oral supplementation. Boosting NAD+ in the bloodstream can be achieved by orally administering NAD+ precursors like nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR). Intaking the recommended doses for these NAD+ precursor supplements have been shown to raise blood NAD+ levels in humans. Furthermore, oral supplements don’t come with the same risks as shots or intravenous administration. 

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