<p>Model: HET3 mice, which are genetically heterogenous to model the diversity of human genetics more precisely than other lab mice, which are usually genetically homogenous </p>
<p>Dosage: 67% reduction in dietary intake of isoleucine </p>


Limiting dietary intake of the amino acid — protein building block — isoleucine significantly extends the lifespan of male mice and modestly extends the lifespan of female mice. 


Aging &amp; Longevity

Nutrition For Longevity: Optimizing Lifespan Through Dietary Choices

Nourishing the body with healthy dietary choices, including caloric restriction, time-restricted feeding, and plant-based diets enhances overall well-being and promotes longevity. 

In the second podcast based on his book LifeSpan, Dr. Sinclair talks about the science behind how fasting and eating certain foods promote longevity.

Researchers from 120 countries converged in an online presentation forum to discuss aging pathways and related therapeutic interventions.

Two thousand two hundred and eighty-six researchers from 120 countries converged in an online meeting to discuss aging pathways and therapeutic strategies to combat aging.

Search Result: Branched Chain Amino Acids

Study Shows Avoiding Consumption of Protein Building Block Isoleucine Increases Lifespan

Nutrition For Longevity: Optimizing Lifespan Through Dietary Choices

David Sinclair: How to Change Your Diet to Live Longer

An International Forum Provides Perspectives on Therapeutics for and Mechanisms of Aging