Model: Humans between the ages of 21 and 72
Dosage: Oral dosage of 500 mg of nicotinamide, 600 mg of alpha lipoic acid, 10 mg of zinc, 20 mg of vitamin C, and 2,110 mg of a botanical blend containing green tea extract, rutin, parsley leaf extract, and black pepper fruit daily for 28 days

A New, Multifaceted Approach to Increasing Cellular NAD+ Levels

British researchers designed a nutraceutical to maximize nicotinamide adenine dinucleotide (NAD+) levels that significantly lowers biological age.

British researchers used a nutraceutical targeting multiple NAD+ biosynthesis- and breakdown-related enzymes to increase NAD+, lower inflammation, and increase sirtuins.

While human studies are needed to determine its true effect on aging, apigenin may improve sleep in anxious individuals.

Apigenin supplement improves sleep of anxious and promotes increases in NAD+ levels. 

Brain &amp; Neurons

Model: C57BL/6J mice and Abca1/g1-m/-m mice of both sexes and bone marrow-derived macrophages from C57BL/6J and Abca1/g1-m/-m mice
Dosage: 300 mg/kg of NMN by daily intraperitoneal injection for two weeks, 5 mg/kg of dasatinib and 50 mg/kg of quercetin by oral gavage for five consecutive days every two weeks for three months, and a 500 μM concentration of NMN for bone marrow-derived macrophages in laboratory dishes

Revitalizing Immune Cells & Eye Function: NMN Study Unveils Remarkable Findings

A new study suggests that NMN reverses an age-associated dysfunctional cellular state — senescence — in immune cells and restores eye function in an age-related eye disease mouse model.

(An anatomical view of an eye with age-related macular degeneration | NAD.com)

NMN reverses an age-related dysfunctional state in immune cells — senescence — and improves eye function in an age-related eye disease mouse model.

2023 Top 10 New Drugs: Weight-loss Wonder Drug Tirzpatide, Strongest "Longevity Drug" Seragon RESTORIN Make the List 

Explore the top 10 new drugs of 2023, featuring breakthroughs like weight-loss wonder Tirzpatide and longevity drug Seragon RESTORIN. Dive into advancements targeting aging, rare diseases, and conditions like Alzheimer's Disease.

Explore the top 10 new drugs of 2023, featuring breakthroughs like weight-loss wonder Tirzpatide and longevity drug Seragon Restorin. Dive into advancements targeting aging, rare diseases, and conditions like Alzheimer's Disease.

Aging &amp; Longevity

An immune system enzyme called CD38 is associated with low NAD+ levels, shortened reproductive lifespan, and fertility problems in female mice.  


Search Result: CD38

A New, Multifaceted Approach to Increasing Cellular NAD+ Levels

Is Apigenin Safe? And How it Improves Sleep and Aging

Revitalizing Immune Cells & Eye Function: NMN Study Unveils Remarkable Findings

2023 Top 10 New Drugs: Weight-loss Wonder Drug Tirzpatide, Strongest “Longevity Elixir” Seragon RESTORIN Make the List

Buck Institute Study Shows Low NAD+ Drives Reproductive Aging and Hinders Fertility