Model: 40 aged patients with COPD with an average age of 71.9 
Dosage: One gram of NR taken twice daily for a total of two grams per day for six weeks

Fresh Insights: NR’s Effects on Inflammation in Age-Related Lung Disease

Taking nicotinamide riboside (NR) is tied to a 52.6% reduction of an inflammatory protein in the sputum—mucus coughed up from the respiratory tract—of patients with chronic obstructive pulmonary disease (COPD).

(Principal investigator Dr. Morten Scheibye-Knudsen, Associate Professor from the University of Copenhagen | Videnskab DK)

Model: C57BL/6J mice
Dosage: 500 mg/kg/day of Urolithin A in food

Supplementing with urolithin A prevents age-related hearing loss and mitochondrial dysfunction in mice. 

Brain &amp; Neurons

Abdominal fat is associated with a dramatic increase in the risk of early death in generally healthy older adults who are not obese. 

(Image: AARP / AHMET YARALI / GETTY IMAGES)

Metabolism

Studies suggest that supplementation with melatonin may slow brain aging, thereby improving cognition. 

Will Interventions that Delay Aging in Animals Work for Humans?

Researchers have shown that using certain agents targeting hallmarks of aging (like inflammation) can extend lifespan in mice, yet human trials are just beginning to uncover whether they work in humans.

(Aged individuals may benefit from aging interventions that work in animal models | NAD.com)

Search Result: NAD supplementation

Fresh Insights: NR’s Effects on Inflammation in Age-Related Lung Disease

Urolithin Anti-Aging Supplement Prevents Hearing Loss, New Research Shows

Abdominal Fat Increases Risk of Early Death by 365% in Non-Obese Adults

Does Melatonin Improve Cognition?

Will Interventions that Delay Aging in Animals Work for Humans?