Model: C57BL/6J mice
Dosage: 500 mg/kg/day of Urolithin A in food

Supplementing with urolithin A prevents age-related hearing loss and mitochondrial dysfunction in mice. 

Brain &amp; Neurons

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation. 

Skin &amp; Muscle

Dr. Mark Hyman, who developed 6-pack abs in his 60s, explains how he ages without disease, including following the Pegan diet — the best of a paleo and vegan diet. 

Longevity expert Dr. Mark Hyman got 6-pack abs in his sixties. To do this, he exercises regularly, practices relaxation techniques, and follows a diet that minimizes elevations in blood sugar levels. 

Aging &amp; Longevity

Model: HSCs derived from the bone marrow of anonymous old adults (58–77 years old); Old mice (81–84 weeks old).
Dosage: Old mice were fed with a control (black) or urolithin A (UA) supplemented (red) diet (50 mg kg/day) for 16 weeks.

Urolithin A Can Revitalize Blood Stem Cells in People and Mice, Study Finds 

This mitochondrial modulator helps old human blood stem cells grow and copy themselves more efficiently, and it also helps blood stem cells make blood and immune systems for old mice. 


Immunity

Model: 24- to 26-month-old male C57BL/6J mice for heart and muscle function experiments
Dosage(oral): 50 mg/kg/day urolithin A

Urolithin A — prevalent in pomegranate — improves the heart health and muscle strength of aged mice by stimulating mitophagy — the destruction of damaged mitochondria. 

CEO of Amazentis (the company that sponsored the study), Chris Rinsch holding a pomegranate (photo: Oliver Evard). 

Discover the amazing story from the University of Washington about how Urolithin A (UA) can make your heart healthy and your muscles super strong. Get the scoop at NAD.com!

Search Result: Urolithin A

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Urolithin A Restores Heart and Muscle Vitality, University of Washington Study