Model: 10-month-old and 22-month-old naturally aged mice / Rats with Partial Discectomy (PDE)-induced Temporomandibular Joint Osteoarthritis (TMJOA).
Dosage: 0.25% αKG and  0.75% αKG
&nbsp;

Longevity Compound Thwarts Age-Related Joint Degeneration

Researchers found that alpha-ketoglutarate (αKG) can treat osteoarthritis by preserving cartilage and reducing joint inflammation. 

Skin &amp; Muscle

The cutoff for vitamin B12 deficiency is too low, according to new findings showing that “normal” B12 levels are associated with neurological deficits in older adults. 


Senior investigator, Ari Green, MD (image: ucsfhealth.org). 

Brain &amp; Neurons

Participants: Physically active and healthy older adults 
Dosage: 1 gram of omega-3s (330 mg EPA plus 660 mg DHA) per day, 2,000 IU of vitamin D per day, and 30 minutes of strength training exercises three times per week

While omega-3 supplementation slows biological aging, adding vitamin D and exercise further slows biological aging.

The “father of aging clocks” and senior study author Steve Horvath, PhD, of Harvard University (Image: quantamagazine.org). 

Aging &amp; Longevity

Participants: Healthy older adults 
Dosage: 4 × 5 g/day of creatine monohydrate for 5 days, followed by 1 × 5 g/day for 23 days

Creatine improves vascular health while lowering blood glucose and triglyceride levels in older adults.

Cardiovascular

Model: 9-month-old male rats 
Dosage: 20 mg/kg of ergothioneine for three weeks

Ergothioneine — a naturally occurring compound found in mushrooms — increases the muscle size of middle-aged rats while extending the lifespan of worms. 


First author of the study, Dunja Petrovic (Image: isas.de)

Search Result: nad supplement

Longevity Compound Thwarts Age-Related Joint Degeneration

Latest Study Finds Recommended Vitamin B12 Dose Is Wrong: How to Get Enough

Harvard Study Reveals that Omega-3s, Vitamin D, and Exercise Additively Slow Biological Aging

New Pilot Study Reveals That Creatine Improves Heart Health

Ergothioneine Boosts NAD+, Mitigates Muscle Aging, and Prolongs Life, New Study Shows