A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases. 

Depiction of microRNA molecules (Image: Artur Plawgo/iStock Photo/MIT.edu). 

Aging &amp; Longevity

Bryan Johnson Injects 300 Million Stem Cells in Latest Longevity Ploy

Bryan Johnson traveled to Cell Colabs in the Bahamas to inject his major joints with 300 million stem cells for enhanced performance and longevity. 

Metabolic Regulators: Improving Energy Production and Expenditure

Metabolic modulators like rapamycin, urolithin A, acarbose, glycine and N-acetyl cysteine, and canagliflozin enhance mitochondrial function to improve metabolism to increase longevity.

(A mitochondria surrounded by a canagliflozin molecule [top left], an acarbose molecule [bottom left], and an N-acetyl cysteine molecule [bottom right])

Explore the impact of metabolic regulators on energy production and expenditure. Discover how these regulators influence cellular metabolism and potentially contribute to improved energy balance and overall health at NAD.com.

Enhancing Energy Production and Expenditure: Role of Metabolic Regulators | NAD

Reviews

Harnessing Stem Cells to Fight Aging

Research has uncovered embryonic, induced pluripotent, and adult stem cell therapies with promising results against age-related neurological, diabetic, and reproductive conditions.

(Blood sample tube containing stem cells | Shutterstock)

Seven different types of stem cells can be used to counter aging-related diseases, but using cellular vesicles associated with their signaling capabilities may be the safest way to harness their therapeutic potential.

Model: C57BL/6 mice
Dosage: Mice received 1 × 1011 vg dose of AAV1.tMCK.NT-3, via intramuscular (IM) injection into the gastrocnemius muscle

New Hospital Study Shows Gene Therapy Reverses Muscle Aging

Researchers show that targeting a growth factor gene in muscle preserves muscle integrity and physical fitness in mice with sarcopenia - the age-related loss of muscle mass and strength. 


Search Result: Cell Differentiation

New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells

Bryan Johnson Injects 300 Million Stem Cells in Latest Longevity Ploy

Metabolic Regulators: Extending Lifespan by Modulating Energy Production and Mitigating Cell Damage

Harnessing Stem Cells to Fight Aging

New Hospital Study Shows Gene Therapy Reverses Muscle Aging