Model: 10-month-old and 22-month-old naturally aged mice / Rats with Partial Discectomy (PDE)-induced Temporomandibular Joint Osteoarthritis (TMJOA).
Dosage: 0.25% αKG and  0.75% αKG
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Longevity Compound Thwarts Age-Related Joint Degeneration

Researchers found that alpha-ketoglutarate (αKG) can treat osteoarthritis by preserving cartilage and reducing joint inflammation. 

Skin &amp; Muscle

Participants: Physically active and healthy older adults 
Dosage: 1 gram of omega-3s (330 mg EPA plus 660 mg DHA) per day, 2,000 IU of vitamin D per day, and 30 minutes of strength training exercises three times per week

While omega-3 supplementation slows biological aging, adding vitamin D and exercise further slows biological aging.

The “father of aging clocks” and senior study author Steve Horvath, PhD, of Harvard University (Image: quantamagazine.org). 

Aging &amp; Longevity

A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases. 

Depiction of microRNA molecules (Image: Artur Plawgo/iStock Photo/MIT.edu). 

Ezra launches a $5,995 longevity scan with Bryan Johnson, using advanced imaging to detect early signs of aging, cancer, and key health risks.









Aside from diet and exercise, senolytics — compounds that remove age-promoting cells — may rejuvenate the immune system and reduce the risk of neurodegeneration and dementia. 

Search Result: EPA

Longevity Compound Thwarts Age-Related Joint Degeneration

Harvard Study Reveals that Omega-3s, Vitamin D, and Exercise Additively Slow Biological Aging

New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells

Would You Pay $6,000 to Know What Might Kill You?

Scientists Reveal How to Slow Brain Aging with Senolytics