The claims of the study in question run contrary to a collection of previous studies, where heart disease risk was actually measured. 

Study has prompted overhyped headlines on news outlets like Newsweek and the New York Post and a high protein diet likely does not increase heart disease risk. 

Cardiovascular

Model: HET3 mice, which are genetically heterogenous to model the diversity of human genetics more precisely than other lab mice, which are usually genetically homogenous 
Dosage: 67% reduction in dietary intake of isoleucine

Limiting dietary intake of the amino acid — protein building block — isoleucine significantly extends the lifespan of male mice and modestly extends the lifespan of female mice. 


Aging &amp; Longevity

Model: Male Wistar rats
Dosage: 2.96 mg/kg/day of resveratrol, 3.56 mg/kg/day of quercetin, 1.76 mg/kg/day of selenium, 2.0 mg/kg/day of omega-3, 3.24 mg/kg/day of ginger, 5.08 mg/kg/day of avocado, 4.44 mg/kg/day of leucine, and 20.0 mg/kg/day of niacin for seven consecutive days before the ischemia-reperfusion procedure

Cocktail of Nutraceuticals with NAD+ Booster Effectively Protects Against Liver Injury

A mixture of nutraceuticals including resveratrol, quercetin, omega-3 fatty acid, selenium, ginger, avocado, leucine, and niacin protects against damage to the liver from reduced blood flow followed by its abrupt restoration in rats.

(The arrow points to dark brown staining for hepatocytes that underwent cell death [apoptosis] with a magnified view of the dead cell in the upper right | Pantanali et al., 2023)

Discover the latest groundbreaking Brazilian study featured on NAD.com, highlighting the potent protective effects of a nutraceutical cocktail combined with an NAD booster against liver injury. Explore how this innovative approach offers promising insights into liver health and well-being.

NAD Booster and Nutraceutical Cocktail: Effective Liver Injury Protection - New Brazilian Study | NAD.com

Nicotinic Acid

Nutrition For Longevity: Optimizing Lifespan Through Dietary Choices

Nourishing the body with healthy dietary choices, including caloric restriction, time-restricted feeding, and plant-based diets enhances overall well-being and promotes longevity. 

Model: 22-23-month-old C57Bl6 male mice and muscle tissue from a healthy, 66-year-old human male
Dosage: 25 µM of metformin and 125 µM of leucine

Metformin and Leucine Cocktail Prevents Muscle Atrophy and Cell Senescence: New Study

Scientists show that combining metformin and leucine prevents mouse and human muscle fiber atrophy along with mouse muscle cell senescence.

(The study’s principal investigator, Micah J. Drummond, PhD | diabetes.org)

The combination of metformin and leucine act synergistically to prevent muscle fiber atrophy, possibly by eliminating senescent cells.

Search Result: Leucine

New Study Claims High Protein Foods Increase Heart Disease Risk — Don’t Believe the Hype

Study Shows Avoiding Consumption of Protein Building Block Isoleucine Increases Lifespan

Cocktail of Nutraceuticals with NAD⁺ Booster Effectively Protects Against Liver Injury: New Brazilian Study

Nutrition For Longevity: Optimizing Lifespan Through Dietary Choices

Metformin and Leucine Cocktail Prevents Muscle Atrophy and Cell Senescence: New Study