Studies suggest that supplementation with melatonin may slow brain aging, thereby improving cognition. 

Brain &amp; Neurons

Bruce N. Ames, PhD, reveals his 11 longevity vitamins — molecules that activate long-term health enzymes — as part of his Triage Theory of aging. 

Triage Theory is named after the assortment system the French Army used during World War I called Triage, which prioritized the treatment of injured soldiers. 

Aging &amp; Longevity

Model: Twenty-five-month-old female Sprague-Dawley rats
Dosage: 1 mL of blood plasma from two-month-old rats intraperitoneally injected every other week until death
Model: C57BL/6J male mice
Dosage: 0.055 mg/mL of ergothioneine administered orally in water from seven weeks of age until death

Canadian Longevity Organization Spotlights Key Research on Latest Anti-Aging Treatments

The Canadian Longevity Association — a non-profit organization dedicated to accelerating longevity research — highlights research on rodent lifespan extension with young plasma and the mushroom-derived compound ergothioneine.

(Canadian Longevity Association | Facebook)

The Canadian Longevity Association presents new findings showing that injecting young plasma into older individuals and mushroom-derived ergothioneine extend lifespan in rodents.

Participants: 50- to 80-year-old individuals 
Dosage: A drink containing 1 × 1010 colony-forming units of Bifidobacterium animalis subsp. lactis GCL2505 and 2.0 g of inulin per 100 g

Middle-aged and older adults showed improvements in cognitive ability after drinking a mixture of probiotics — beneficial bacteria — and fiber. 


Model: Humans aged 50 to 90 years with mild cognitive impairment or mild dementia due to Alzheimer’s disease
Dosage: 10 mg/kg lecanemab once every two weeks via intravenous (vein) injection
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Breakthrough Alzheimer's Treatment Achieves Historic FDA Stamp of Approval

In June of 2023, The FDA granted the drug lecanemab (leqembi) traditional approval for the treatment of Alzheimer’s. 

Search Result: Mild Cognitive Impairment

Does Melatonin Improve Cognition?

Bruce Ames’ Triage Theory & The Eleven Longevity Vitamins

Canadian Longevity Organization Spotlights Key Research on Young Plasma and Mushroom-Based Anti-Aging Treatments

Probiotic and Fiber Drink Deters Dementia in New Japanese Study

Breakthrough Alzheimer’s Treatment Achieves Historic FDA Stamp of Approval