Model: Male Monkeys 
Dosage: 20 mg/kg/day of metformin

Supplementation of metformin — a first-line treatment for type 2 diabetes and the second-most prescribed medication in the U.S. — improves the learning and memory of older monkeys. 

Brain &amp; Neurons

Bryan Johnson Injects 300 Million Stem Cells in Latest Longevity Ploy

Bryan Johnson traveled to Cell Colabs in the Bahamas to inject his major joints with 300 million stem cells for enhanced performance and longevity. 

Aging &amp; Longevity

Bryan Johnson Edits His Genes To Live Past 120 

Tech mogul Bryan Johnson undergoes follistatin gene therapy to explore its potential for extending human lifespan beyond 120 years.


Model: 18-month-old C57BL/6J mice 
Dose (oral): 5 mg/kg of dasatinib combined with 50 mg/kg of quercetin

Senolytics Restore Age-Related Heart-Brain Connection Loss

Treating old mice with two senolytics — compounds that remove senescent (dysfunctional) cells —  called dasatinib and quercetin prevents heart-brain connection loss and irregular heart rhythms.  


Principal Investigator Dr. Stefanie Dimmeler | DZHK 

Cardiovascular

According to a new scientific review, sarcopenia — age-related muscle loss — can potentially be mitigated by replenishing NAD+. 


Search Result: Muscle Regeneration

Metformin Slows Brain Aging in Older Monkeys, New Research Shows

Bryan Johnson Injects 300 Million Stem Cells in Latest Longevity Ploy

Bryan Johnson Edits His Genes To Live Past 120

German Study Shows Senolytics Restore Heart-Brain Connection to Reverse Cardiac Aging

Can Boosting NAD+ Prevent Muscle Loss with Age?