Model: 9-month-old male rats 
Dosage: 20 mg/kg of ergothioneine for three weeks

Ergothioneine — a naturally occurring compound found in mushrooms — increases the muscle size of middle-aged rats while extending the lifespan of worms. 


First author of the study, Dunja Petrovic (Image: isas.de)

Skin &amp; Muscle

Columbia University scientists find that senolytics — compounds that remove age-promoting cells — restore hair follicle regeneration in a human cell/mouse model. 

Leading aging biology expert, Morgan Levine, Ph.D., says the scientific field of aging has a “major gender balance issue.”


Dr. Morgan Levine (image: Nicole Frappier/ The Guardian)

Morgan Levine triggers a flurry of responses on Twitter/X by saying there is gender imbalance in the field of aging biology. 

Others

Pinpointing the Causes of Aging: Sifting Through Prevailing Theories

DNA damage, telomere shortening, and altered DNA methylation all contribute to aging. Here is what you can do about it.

Potential contributors to aging include accumulated DNA damage, telomere shortening, and altered DNA molecular tagging patterns (methylation), and a researcher from the UK shares evidence for their causal roles.

Aging &amp; Longevity

Model: Male Wistar rats
Dosage: 2.96 mg/kg/day of resveratrol, 3.56 mg/kg/day of quercetin, 1.76 mg/kg/day of selenium, 2.0 mg/kg/day of omega-3, 3.24 mg/kg/day of ginger, 5.08 mg/kg/day of avocado, 4.44 mg/kg/day of leucine, and 20.0 mg/kg/day of niacin for seven consecutive days before the ischemia-reperfusion procedure

Cocktail of Nutraceuticals with NAD+ Booster Effectively Protects Against Liver Injury

A mixture of nutraceuticals including resveratrol, quercetin, omega-3 fatty acid, selenium, ginger, avocado, leucine, and niacin protects against damage to the liver from reduced blood flow followed by its abrupt restoration in rats.

(The arrow points to dark brown staining for hepatocytes that underwent cell death [apoptosis] with a magnified view of the dead cell in the upper right | Pantanali et al., 2023)

Discover the latest groundbreaking Brazilian study featured on NAD.com, highlighting the potent protective effects of a nutraceutical cocktail combined with an NAD booster against liver injury. Explore how this innovative approach offers promising insights into liver health and well-being.

Search Result: NAD manipulation

Ergothioneine Boosts NAD+, Mitigates Muscle Aging, and Prolongs Life, New Study Shows

Can Senolytic Supplements Restore Hair Growth? What the New Research Says

Female Longevity Scientist Points Out Gender Imbalance in Aging Field

Pinpointing the Causes of Aging: Sifting Through Prevailing Theories

Cocktail of Nutraceuticals with NAD⁺ Booster Effectively Protects Against Liver Injury: New Brazilian Study