Model: 24-month-old female Sprague Dawley rats
Dosage: Undisclosed doses of pig-derived exosomes were injected into the rats every-other-day for eight days starting at day 1 and recommencing at days 68, 181, 280, and 377

Nano-Sized Vesicle Infusions Break Rat Lifespan Record

Nano-sized vesicles called exosomes derived from pig blood plasma significantly extended rat lifespan and broke the record for the longest-living rat.

(An image of Sima, the longest-recorded living rat, at 47 months of age | The Guardian)

Aging &amp; Longevity

The Science Behind Steve Aoki's Biohacking Regimen for Peak Performance

DJ Steve Aoki follows a comprehensive biohacking regimen to optimize his health, lower his biological age, and be the ultimate performer.

Longevity Expert Answers Aging Questions from X 

Levine answers questions about the latest aging biology research from social media posts. 


Morgan Levine, Ph.D. (image: USC Leonard Davis School of Gerontology). 

Longevity scientists Morgan Levine answers questions on aging from X. 

David Sinclair: DNA Tagging, rather than DNA Damage, Drives Aging and Is Reversible

Sinclair’s theory proposes that aging occurs due to the loss of epigenetic information — patterns of DNA molecular tags that influence gene activity — which can be restored to a more intact, youthful state.

(Harvard University | blog.logomyway.com)

Harvard professor David Sinclair’s Information Theory of Aging posits that epigenetic information loss facilitates aging.

Epigenetics

Model: 16-month-old male C57BL/6 mice 
Dosage (oral): 5 mg/kg of dasatinib and 50 mg/kg of quercetin biweekly for 4 months

Senolytic Treatment Rejuvenates Intestines 

The senolytic — compound that eliminates aged cells — combo dasatinib and quercetin (D+Q) promotes small intestine regeneration in aged mice. 


A fluorescent image of the intestinal wall of an aged mouse. Dead cells (red) are depicted among normal (blue) cells. 

Search Result: Tissue Rejuvenation

Nano-Sized Vesicle Infusions Break Rat Lifespan Record

The Science Behind Steve Aoki’s Biohacking Regimen for Peak Performance

Altos Labs’ Dr. Morgan Levine Answers the Internet’s Most Burning Questions on Aging

David Sinclair: DNA Tagging, rather than DNA Damage, Drives Aging and Is Reversible

Leveraging Nutrient Uptake to Slow Aging: Research Reveals Senolytic Treatment Rejuvenates Intestines