<p>Model: 16-month-old female C57BL/6 mice </p>
<p>Dosage: 60 mg/kg/day of ABT-263 dissolved in drinking water for 7 days on, 7 days off, and 7 days on again </p>


A senolytic compound and anti-cancer drug called ABT-263 accelerates ovarian aging in aged mice, suggesting it promotes infertility. 

Others

Six Intriguing Ideas from David Sinclair’s Book, Lifespan

In his book, Harvard’s Dr. David Sinclair presents concepts such as the Information Theory of Aging — how modifications to our DNA may cause aging.

(Lifespan: Why We Age — and Why We Don’t Have To | booko.com.au)

Harvard’s Dr. David Sinclair presents six thrilling ideas in his book Lifespan, which include his Information Theory of Aging — changes to chemical modifications on DNA that underlie all aging processes.

Aging &amp; Longevity

Liver King's 9 Ancestral Tenets for Health and Longevity: Science or Fad?

Liver King's 9 Ancestral Tenants strive to enhance longevity by combining ancient wisdom and modern health practices.

Explore the science behind Liver King's 9 Ancestral Tenets. Take a closer look into his blend of ancient wisdom and modern health in his quest for longevity.

Based on human evidence, Harvard and MIT scientists determine the most promising anti-aging interventions, including NAD+ precursors, spermidine, and senolytics. 


MIT’s Leonard Guarente, Ph.D. (image: amacad.org), Harvard’s David Sinclair, Ph.D. (image: buckinstitute.org), and University of Paris Descartes’ Guido Kromer, Ph.D., M.D. (image: createcures.org). 

David Sinclair and fellow top aging biology researchers review clinical trials pertaining to the eight anti-aging compounds. 

Combined senolytics dasatinib and quercetin (D+Q) — compounds that remove age-driving cells — rejuvenate the proliferation of sperm stem cells. 


Aged mice have fewer sperm cells than young mice, similar to humans. 

Search Result: fertility research

Which Anti-Aging Senolytic Supplement Should You Avoid?

Six Intriguing Ideas from David Sinclair’s Book, Lifespan: Why We Age — and Why We Don’t Have To

Liver King’s 9 Ancestral Tenets for Health and Longevity: Science or Fad?

David Sinclair and Colleagues Summarize 8 Anti-Aging Medicines Applicable to Humans

Senolytics Enhance Male Reproductive Potential by Rejuvenating Sperm Stem Cells: Japan Study