Participants: Physically active and healthy older adults 
Dosage: 1 gram of omega-3s (330 mg EPA plus 660 mg DHA) per day, 2,000 IU of vitamin D per day, and 30 minutes of strength training exercises three times per week

While omega-3 supplementation slows biological aging, adding vitamin D and exercise further slows biological aging.

The “father of aging clocks” and senior study author Steve Horvath, PhD, of Harvard University (Image: quantamagazine.org). 

Aging &amp; Longevity

Model: 9-month-old male rats 
Dosage: 20 mg/kg of ergothioneine for three weeks

Ergothioneine — a naturally occurring compound found in mushrooms — increases the muscle size of middle-aged rats while extending the lifespan of worms. 


First author of the study, Dunja Petrovic (Image: isas.de)

Skin &amp; Muscle

Model: Male Sprague Dawley rats
Dosage: 1.5 mg/kg body or rapamycin injected 3 times a week for 4 weeks

The longevity-associated drug rapamycin diminishes muscle size and strength in young rats when compared to untreated but calorically restricted young rats. 

Columbia University scientists find that senolytics — compounds that remove age-promoting cells — restore hair follicle regeneration in a human cell/mouse model. 

Betaine Supplement Prevents Age-Related Loss of Muscle Size and Strength

Betaine prevents loss of muscle mass and strength while enhancing autophagy in old mice.

Search Result: supplements

Harvard Study Reveals that Omega-3s, Vitamin D, and Exercise Additively Slow Biological Aging

Ergothioneine Boosts NAD+, Mitigates Muscle Aging, and Prolongs Life, New Study Shows

If Too Young, Rapamycin Isn’t the Anti-Aging Remedy for You, Says New Research

Can Senolytic Supplements Restore Hair Growth? What the New Research Says

Betaine Supplement Prevents Age-Related Loss of Muscle Size and Strength