Model: Humans between the ages of 21 and 72
Dosage: Oral dosage of 500 mg of nicotinamide, 600 mg of alpha lipoic acid, 10 mg of zinc, 20 mg of vitamin C, and 2,110 mg of a botanical blend containing green tea extract, rutin, parsley leaf extract, and black pepper fruit daily for 28 days

A New, Multifaceted Approach to Increasing Cellular NAD+ Levels

British researchers designed a nutraceutical to maximize nicotinamide adenine dinucleotide (NAD+) levels that significantly lowers biological age.

British researchers used a nutraceutical targeting multiple NAD+ biosynthesis- and breakdown-related enzymes to increase NAD+, lower inflammation, and increase sirtuins.

A potentially transformative antibody that inhibits the IL-11 protein increases mouse lifespan by 22% by targeting the same pathways as metformin and rapamycin. 

Antibody prolongs the lifespan of mice by 22%. 

Aging &amp; Longevity

Model: C57BL/6 mice and Zpmste24-deficient progeria mice
Dosage: .03% w/w of canagliflozin mixed into diets from day 3 to 20 weeks

Japanese Study: Common Diabetes Drug Clears Senescent Cells and Extends Lifespan

Japanese scientists uncover that a diabetes drug called canagliflozin removes senescent cells and moderately extends lifespan in a mouse model of premature aging.

(A laboratory mouse alongside the molecular structure of canagliflozin | NAD.com)

The diabetes medication canagliflozin clears senescent cells and extends lifespan in a mouse model of premature aging called progeria.

Six Intriguing Ideas from David Sinclair’s Book, Lifespan

In his book, Harvard’s Dr. David Sinclair presents concepts such as the Information Theory of Aging — how modifications to our DNA may cause aging.

(Lifespan: Why We Age — and Why We Don’t Have To | booko.com.au)

Harvard’s Dr. David Sinclair presents six thrilling ideas in his book Lifespan, which include his Information Theory of Aging — changes to chemical modifications on DNA that underlie all aging processes.

Nutrition For Longevity: Optimizing Lifespan Through Dietary Choices

Nourishing the body with healthy dietary choices, including caloric restriction, time-restricted feeding, and plant-based diets enhances overall well-being and promotes longevity. 

Search Result: AMPK

A New, Multifaceted Approach to Increasing Cellular NAD+ Levels

Anti-Aging Antibody Significantly Extends Life by 22% in Breakthrough Study

Japanese Study: Common Diabetes Drug Clears Senescent Cells and Extends Lifespan

Six Intriguing Ideas from David Sinclair’s Book, Lifespan: Why We Age — and Why We Don’t Have To

Nutrition For Longevity: Optimizing Lifespan Through Dietary Choices