Will Interventions that Delay Aging in Animals Work for Humans?

Researchers have shown that using certain agents targeting hallmarks of aging (like inflammation) can extend lifespan in mice, yet human trials are just beginning to uncover whether they work in humans.

(Aged individuals may benefit from aging interventions that work in animal models | NAD.com)

Aging &amp; Longevity

<p>Model: Male Monkeys </p>
<p>Dosage: 20 mg/kg/day of metformin </p>


Supplementation of metformin — a first-line treatment for type 2 diabetes and the second-most prescribed medication in the U.S. — improves the learning and memory of older monkeys. 

Brain &amp; Neurons

Four FDA-Approved Drugs that Reduce Chances of Aging-Related Death

Dr. Nir Barzilai, the director of aging research at Albert Einstein College of Medicine, discusses the science behind SGLT2 inhibitors, metformin, bisphosphonates, and GLP-1 agonists.

Dr. Nir Barzilai, the director of aging research at Albert Einstein College of Medicine, relays that we have four FDA-approved drugs that lower human mortality: SGLT2 inhibitors, bisphosphonates, metformin, and GLP-1 agonists.

Bryan Johnson Edits His Genes To Live Past 120 

Tech mogul Bryan Johnson undergoes follistatin gene therapy to explore its potential for extending human lifespan beyond 120 years.


AI may be capable of discovering drugs that target the multitude of biological processes thought to underlie the aging process.  

AI may identify new targets for anti-aging drugs that humans may have overlooked. 

Search Result: Aging Therapeutics

Will Interventions that Delay Aging in Animals Work for Humans?

Metformin Slows Brain Aging in Older Monkeys, New Research Shows

Four FDA-Approved Drugs that Reduce Chances of Aging-Related Death

Bryan Johnson Edits His Genes To Live Past 120

How Scientists Plan to Cure Aging with AI