2023 Top 10 New Drugs: Weight-loss Wonder Drug Tirzpatide, Strongest "Longevity Drug" Seragon RESTORIN Make the List 

Explore the top 10 new drugs of 2023, featuring breakthroughs like weight-loss wonder Tirzpatide and longevity drug Seragon RESTORIN. Dive into advancements targeting aging, rare diseases, and conditions like Alzheimer's Disease.

Explore the top 10 new drugs of 2023, featuring breakthroughs like weight-loss wonder Tirzpatide and longevity drug Seragon Restorin. Dive into advancements targeting aging, rare diseases, and conditions like Alzheimer's Disease.

Aging &amp; Longevity

Model: APP/PS1 Alzheimer&#8217;s Disease mice
Dosage: 10 mg/kg/day Au NPs

A new study showed that when mice with Alzheimer’s disease ate gold particles, they had less brain inflammation and cognitive decline.

Brain &amp; Neurons

Model: Senescence-accelerated mouse prone 8 (SAMP8) mice
Dosage: 5 mg/kg per day of oral trigonelline

New Study Reveals Coffee-Derived Molecule Trigonelline Defends Against Cognitive Decline

Japanese researchers have demonstrated that trigonelline can prevent learning and memory impairment, reduce neuroinflammation, and replenish neurotransmitter levels in a mouse model of accelerated aging.

(A ring of coffee beans surrounding a trigonelline molecule | NAD.com)

Learn how a new study uncovers the incredible power of a molecule found in coffee, called Trigonelline, in defending against forgetfulness and keeping your brain sharp. Get the scoop at NAD.com!

Amazing News about Coffee: Trigonelline Fights Against Forgetfulness! | NAD

Model: 5xFAD Alzheimer&#8217;s model mice
Dosage (oral): 20 mg/kg VBIT-4

Cognitive deficits, neurodegeneration, and neuroinflammation are prevented in an Alzheimer’s mouse model with a new drug that targets VDAC1 — a protein that transports molecules like NAD+ to and from mitochondria. 


Principal Investigator Dr. Varda Shoshan-Barmatz | NIBN 

Explore the findings of a groundbreaking study conducted by Israeli scientists, revealing the potential of manipulating an NAD-linked protein in curbing Alzheimer's disease symptoms. Discover the promising advancements in Alzheimer's research and the role of NAD in combating this neurodegenerative condition. Read more on NAD.

Groundbreaking Study: Israeli Scientists Curb Alzheimer's Symptoms by Manipulating an NAD-Linked Protein - NAD

Senolytics: Clearing Troublesome Senescent Cells for Revitalized Aging

Senolytics selectively eliminate senescent cells — non-proliferative cells that release inflammatory molecules to surrounding tissue triggering otherwise healthy cells to enter senescence.

Senolytics, including dasatinib and quercetin along with fisetin, selectively eliminate aged, non-proliferative cells (senescent cells) to revitalize organ health and alleviate age-associated diseases.

Search Result: Alzheimer's symptoms

2023 Top 10 New Drugs: Weight-loss Wonder Drug Tirzpatide, Strongest “Longevity Elixir” Seragon RESTORIN Make the List

Researchers Use Gold Nanoparticles to Treat Neurodegenerative Disease

New Study Reveals Coffee-Derived Molecule Trigonelline Defends Against Cognitive Decline

Israeli Scientists Find Potential Breakthrough Drug for Alzheimer’s

Senolytics: Clearing Troublesome Senescent Cells for Body Revitalization