The longevity gene klotho prolongs the lifespan of mice while preventing muscle, bone, and brain aging. 

Miguel Chillón, PhD, and Laura Rodriguez-Estevez, researchers from Universitat Autònoma de Barcelona in Spain, who conducted the study (image: uab.cat) 

Aging &amp; Longevity

Dr. Sinclair and collaborators show that an age-reversal technology that rejuvenates cells protects neurons from inflammation and cell death in mice. 

Brain &amp; Neurons

A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases. 

Depiction of microRNA molecules (Image: Artur Plawgo/iStock Photo/MIT.edu). 

<p>Model: 9-month-old male rats </p>
<p>Dosage: 20 mg/kg of ergothioneine for three weeks </p>


Ergothioneine — a naturally occurring compound found in mushrooms — increases the muscle size of middle-aged rats while extending the lifespan of worms. 


First author of the study, Dunja Petrovic (Image: isas.de)

Skin &amp; Muscle

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging

The longevity biotech company, MetaShape, has a new compound designed to restore cellular nicotinamide adenine dinucleotide (NAD+) and offset elevated cholesterol, cognitive decline, and neurodegeneration.

Search Result: Cellular regeneration

One-Time Anti-Aging Gene Therapy Treatment Prolongs Life by 20%, New Study Shows

Age-Reversal Tech Protects Against Neurodegeneration in Latest David Sinclair Study

New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells

Ergothioneine Boosts NAD+, Mitigates Muscle Aging, and Prolongs Life, New Study Shows

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging