Removing an NAD+ transporter called SLC25A51 from insulin-secreting cells mitigates diabetes and reduces senescent cells — cells that contribute to the pathology of age-related diseases.  


Principal investigator Nora Kory, PhD, from Harvard University (image: harvard.edu). 

<p>Model: Type 2 diabetic rats induced by high-fat diet and low-dose streptozotocin (STZ)<br data-start="188" data-end="191" data-is-only-node="" />Dosage: 0.2 mg/kg liraglutide administered daily for 8 weeks</p>


Weight Loss Drug Protects Against Diabetic Sarcopenia: New Study Finds

Researchers show that liraglutide protects muscle from diabetes-induced atrophy by reversing cellular aging and activating the YAP/TAZ signaling pathway.

Diabetes &amp; Obesity

Esteemed Cardiologist Says Commercial Interests Are Distorting Evidence Behind Statins

Dr. Aseem Malhotra, a cardiologist from the UK, says pharmaceutical company-sponsored research distorts the scientific evidence behind the effectiveness of cholesterol-lowering statins against heart disease.

(Dr. Aseem Malhotra, cardiologist | The Telegraph)

Cardiovascular

Aside from diet and exercise, senolytics — compounds that remove age-promoting cells — may rejuvenate the immune system and reduce the risk of neurodegeneration and dementia. 

Brain &amp; Neurons

Supplementing with ergothioneine — a compound found in lion’s mane mushrooms — enhances the verbal memory of elderly individuals. 

(Image: marthastewart.com) Lion’s mane mushrooms.

Search Result: D Q

Harvard Scientists Unravel the Role of NAD+ Transporter in Mitigating Age-Related Diabetes

Weight Loss Drug Protects Against Diabetic Sarcopenia: New Study Finds

Activist Cardiologist Says Commercial Interests Are Distorting Evidence Behind Statins

Scientists Reveal How to Slow Brain Aging with Senolytics

Ergothioneine Longevity Supplement Enhances Verbal Memory