Model: 5xFAD mice
Dosage: 5-µL sprayed into each nostril at concentrations of 30 × 109/100 µL once weekly for two weeks

Exploring a Nasal Spray that Might Delay Alzheimer’s Progression by Years

Researchers use nano-sized vesicles derived from neural stem cells to preserve cognition as well as reduce brain inflammation and plaque buildup in an Alzheimer’s mouse model.

(An aged woman using an intranasal spray to avert Alzheimer's disease progression | NAD.com)

Brain &amp; Neurons

Bryan Johnson Injects 300 Million Stem Cells in Latest Longevity Ploy

Bryan Johnson traveled to Cell Colabs in the Bahamas to inject his major joints with 300 million stem cells for enhanced performance and longevity. 

Aging &amp; Longevity

Model: 5XFAD transgenic mouse model for Alzheimer&#8217;s disease 
Dosage: Intravenous administration of 200 μl extracellular vesicles (0.5 μg/μl concentration)

 Particles secreted from stem cells called extracellular vesicles (EVs) counter memory loss and neurodegeneration in an Alzheimer’s disease mouse model.  


Principal Investigator Dr. Jialin Zheng | Tongji University School of Medicine 

Particles secreted from stem cells called extracellular vesicles (EVs) prolong the lifespan of old rats while improving their exercise capacity and heart function. 

Principal Investigator Eduardo Marban, M.D., Ph.D. | Cedars-Sinai Medical Center 

Discover groundbreaking research from Cedars-Sinai Medical Center where scientists have successfully prolonged lifespan using vesicles secreted by stem cells. Explore the fascinating findings at NAD.com.

Cedars-Sinai Scientists Extend Lifespan with Stem Cell-Secreted Vesicles | NAD

Model: C57BL/6J Mice
Dosage: 20 ug of sEVs’ protein on days 1 and 14 of experiment

Particles Secreted from Stem Cells Significantly Reduce Aging

University of Valencia researchers use small vesicles (sEVs) derived from young stem cells (ADSC) to reduce frailty, regulate inflammation, and lower senescence - a critical dormant state of cell-cycle arrest that drives aging. 


Senior author, Dr. Consuelo Borras | INCLIVA

University of Valencia researchers use small vesicles (sEVs) derived from young stem cells (ADSC) to reduce frailty, regulate inflammation, and lower senescence - a critical dormant state of cell-cycle arrest that drives aging. 

Search Result: Extracellular vesicles

Exploring a Nasal Spray that Might Delay Alzheimer’s Progression by Years

Bryan Johnson Injects 300 Million Stem Cells in Latest Longevity Ploy

Study Shows Stem Cell-Secreted Particles Can Reverse Alzheimer’s

Cedars-Sinai Scientists Identify Stem Cell-Secreted Particles that Boost Lifespan and Endurance

New Study Shows Particles Secreted from Stem Cells Significantly Reduce Aging