Multi-Nation Expert Panel Agrees On Biomarkers of Aging

For the first time, a multi-nation panel of aging experts reached a consensus to designate markers of aging, which could make aging intervention testing easier.

(An aged individual holding pills and supplements meant to work against aging | UCLA)

Aging &amp; Longevity

Model: 10-month-old and 22-month-old naturally aged mice / Rats with Partial Discectomy (PDE)-induced Temporomandibular Joint Osteoarthritis (TMJOA).
Dosage: 0.25% αKG and  0.75% αKG
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Longevity Compound Thwarts Age-Related Joint Degeneration

Researchers found that alpha-ketoglutarate (αKG) can treat osteoarthritis by preserving cartilage and reducing joint inflammation. 

Skin &amp; Muscle

Dr. Sinclair and collaborators show that an age-reversal technology that rejuvenates cells protects neurons from inflammation and cell death in mice. 

Brain &amp; Neurons

Stanford Study: Infusing Aged Surgery Patients with Young Plasma Reduces Inflammation

In a first proof of principle human trial, researchers demonstrated that plasma proteins from young donors lower inflammatory markers in elderly people who underwent surgery.

Clinical Trials

A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases. 

Depiction of microRNA molecules (Image: Artur Plawgo/iStock Photo/MIT.edu). 

Search Result: Inflammation

Expert Panel Agrees On Biomarkers of Aging for Testing Therapeutics

Longevity Compound Thwarts Age-Related Joint Degeneration

Age-Reversal Tech Protects Against Neurodegeneration in Latest David Sinclair Study

Stanford Study: Infusing Aged Patients with Young Plasma Reduces Inflammation After Surgery

New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells