Model: 5xFAD mice
Dosage: 5-µL sprayed into each nostril at concentrations of 30 × 109/100 µL once weekly for two weeks

Exploring a Nasal Spray that Might Delay Alzheimer’s Progression by Years

Researchers use nano-sized vesicles derived from neural stem cells to preserve cognition as well as reduce brain inflammation and plaque buildup in an Alzheimer’s mouse model.

(An aged woman using an intranasal spray to avert Alzheimer's disease progression | NAD.com)

Brain &amp; Neurons

Abdominal fat is associated with a dramatic increase in the risk of early death in generally healthy older adults who are not obese. 

(Image: AARP / AHMET YARALI / GETTY IMAGES)

Metabolism

Bruce N. Ames, PhD, reveals his 11 longevity vitamins — molecules that activate long-term health enzymes — as part of his Triage Theory of aging. 

Triage Theory is named after the assortment system the French Army used during World War I called Triage, which prioritized the treatment of injured soldiers. 

Aging &amp; Longevity

Model: 24-month-old female Sprague Dawley rats
Dosage: Undisclosed doses of pig-derived exosomes were injected into the rats every-other-day for eight days starting at day 1 and recommencing at days 68, 181, 280, and 377

Nano-Sized Vesicle Infusions Break Rat Lifespan Record

Nano-sized vesicles called exosomes derived from pig blood plasma significantly extended rat lifespan and broke the record for the longest-living rat.

(An image of Sima, the longest-recorded living rat, at 47 months of age | The Guardian)

NAD+ is “The Future” of Longevity: What Celebrities are Doing to “Never Age”

Celebrities like Hailey Bieber, Jennifer Aniston, and Shannon Sharpe have endorsed NAD+ therapy, and studies suggest it could be an effective anti-aging intervention. 

Search Result: RNA

Exploring a Nasal Spray that Might Delay Alzheimer’s Progression by Years

Abdominal Fat Increases Risk of Early Death by 365% in Non-Obese Adults

Bruce Ames’ Triage Theory & The Eleven Longevity Vitamins

Nano-Sized Vesicle Infusions Break Rat Lifespan Record

NAD+ is “The Future” of Longevity: What Celebrities are Doing to “Never Age”