Model: Type 2 diabetic rats induced by high-fat diet and low-dose streptozotocin (STZ) Dosage: 0.2 mg/kg liraglutide administered daily for 8 weeks

Weight Loss Drug Protects Against Diabetic Sarcopenia: New Study Finds

Researchers show that liraglutide protects muscle from diabetes-induced atrophy by reversing cellular aging and activating the YAP/TAZ signaling pathway.

Diabetes &amp; Obesity

Multi-Nation Expert Panel Agrees On Biomarkers of Aging

For the first time, a multi-nation panel of aging experts reached a consensus to designate markers of aging, which could make aging intervention testing easier.

(An aged individual holding pills and supplements meant to work against aging | UCLA)

Aging &amp; Longevity

Stop Fast Aging! New Research Suggests Protecting One Organ Helps All

Researchers from University College London unveil data suggesting that accelerated aging in certain organs increases the risk of age-related diseases across other organs.

(University College London | The Independent)

A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases. 

Depiction of microRNA molecules (Image: Artur Plawgo/iStock Photo/MIT.edu). 

Model: C57BL/6N mice 
Dosage: 1 g/kg carvedilol in food for one week followed by four weeks of PAGln treatment, consisting of 50 mg/kg per day by injection, and the same PAGln treatment for four weeks followed by 50 mg/kg per day of ABT263 via oral gavage for five days

New Study Suggests Combining Senolytics with Blood Pressure Medication Counteracts an Aging Gut

Carvedilol, a blood pressure medication, and the senolytic agent ABT-263 both attenuate cellular senescence—an age-related, dysfunctional cellular state—driven by a gut bacterial metabolite in mice.

Search Result: kidney damage

Weight Loss Drug Protects Against Diabetic Sarcopenia: New Study Finds

Expert Panel Agrees On Biomarkers of Aging for Testing Therapeutics

Stop Fast Aging! New Research Suggests Protecting One Organ Helps All

New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells

Combining Senolytics with Blood Pressure Medication Counteracts Gut Aging and Promotes Longevity, Suggests New Study