Nutrition For Longevity: Optimizing Lifespan Through Dietary Choices

Nourishing the body with healthy dietary choices, including caloric restriction, time-restricted feeding, and plant-based diets enhances overall well-being and promotes longevity. 

Aging &amp; Longevity

Scientists Identify Hallmarks of Aging that Can Be Reversed 

Twelve underlying drivers of aging can potentially be slowed, prevented, or reversed to improve health and extend lifespan. 

Investigators Dr. Guido Kroemer (left) and Dr. Carlos Lopez-Otin (right) | El Comercio 

Reviews

Model: C57BL/6J
Dosage: Intraperitoneal (IP) injection of Met (50 mg/kg body weight/day, 
100 μl of 10 mg/ml metformin/mouse/day) for 8 weeks

Study Shows Metformin Prevents Connective Tissue Aging 

Metformin, a common diabetes medication, prevents the degradation of tendons – connective tissue between muscles and bones – by blocking cell aging and inflammation. 

Female KunMing Mice (2 months old, weight 20~25 g)
Metformin: 100 or 300 mg/kg/day for 6 weeks

Metformin Reverses Age-Related Immune System Decline 

Researchers from Zhengzhou University utilize metformin to attenuate the degeneration of the thymus - an immune organ that plays a vital role in the development and function of immune fighting cells (T cells). 


Metformin, a diabetes drug, shows promise in preserving thymus function and structure in aging mice by enhancing mitochondrial function and reducing senescent cells.

Immunity

In a human clinical trial, Yale scientists find that caloric restriction prevents thymus shrinkage and changes the inflammatory profile of fat tissue. 

Search Result: thymus

Nutrition For Longevity: Optimizing Lifespan Through Dietary Choices

The Hallmarks of Aging and How To Target Them

Study Shows Metformin Prevents Connective Tissue Aging

New Study Shows Metformin Reverses Age-Related Thymus Degeneration by Boosting Mitochondrial Function

Caloric Restriction Decreases Inflammation in Humans