Will Interventions that Delay Aging in Animals Work for Humans?

Researchers have shown that using certain agents targeting hallmarks of aging (like inflammation) can extend lifespan in mice, yet human trials are just beginning to uncover whether they work in humans.

(Aged individuals may benefit from aging interventions that work in animal models | NAD.com)

Aging &amp; Longevity

Scientists cure type 2 diabetes by replicating the function of the pancreas with stem cells. 


Diabetes &amp; Obesity

<p>Model: Male Monkeys </p>
<p>Dosage: 20 mg/kg/day of metformin </p>


Supplementation of metformin — a first-line treatment for type 2 diabetes and the second-most prescribed medication in the U.S. — improves the learning and memory of older monkeys. 

Brain &amp; Neurons

Four FDA-Approved Drugs that Reduce Chances of Aging-Related Death

Dr. Nir Barzilai, the director of aging research at Albert Einstein College of Medicine, discusses the science behind SGLT2 inhibitors, metformin, bisphosphonates, and GLP-1 agonists.

Dr. Nir Barzilai, the director of aging research at Albert Einstein College of Medicine, relays that we have four FDA-approved drugs that lower human mortality: SGLT2 inhibitors, bisphosphonates, metformin, and GLP-1 agonists.

A potentially transformative antibody that inhibits the IL-11 protein increases mouse lifespan by 22% by targeting the same pathways as metformin and rapamycin. 

Antibody prolongs the lifespan of mice by 22%. 

Search Result: Metformin

Will Interventions that Delay Aging in Animals Work for Humans?

2024 Breakthrough: Type 2 Diabetes Cure

Metformin Slows Brain Aging in Older Monkeys, New Research Shows

Four FDA-Approved Drugs that Reduce Chances of Aging-Related Death

Anti-Aging Antibody Significantly Extends Life by 22% in Breakthrough Study