Participants: healthy adults between the ages of 50 and 81
Dosage: 5 mg/week or 10 mg/week of rapamycin

One of the most potent anti-aging compounds rapamycin — an FDA-approved drug that inhibits mTOR — increases the lean body mass of older women while reducing their pain. 


Senior investigator Sajad Zalzala, MD (image: cnbc.com)

Clinical Trials

Cognitive deficits were reduced by 52% in Alzheimer’s disease patients receiving transcranial magnetic stimulation (TMS) — a technique that stimulates the brain’s electrical activity. 


Lead researcher Giocomo Koch, MD, PhD, uses a TMS device on an individual wearing an electroencephalogram (EEG) cap (image: domussantarita.it). 

Brain &amp; Neurons

The most comprehensive brain model reveals that combining NAD+ (nicotinamide adenine dinucleotide) supplementation with diet and exercise powerfully modulates brain aging. 


Model: Type 2 diabetic rats induced by high-fat diet and low-dose streptozotocin (STZ) Dosage: 0.2 mg/kg liraglutide administered daily for 8 weeks

Weight Loss Drug Protects Against Diabetic Sarcopenia: New Study Finds

Researchers show that liraglutide protects muscle from diabetes-induced atrophy by reversing cellular aging and activating the YAP/TAZ signaling pathway.

Diabetes &amp; Obesity

Longevity Fanatic Bryan Johnson’s Daily Aging Intervention Routine for 2025

Aging guru Bryan Johnson shares his latest daily longevity protocol, which he uses to optimize measurements of his body’s aging.

(A futuristic image of Bryan Johnson | YouTube)

Venture capitalist and aging guru Bryan Johnson reveals his latest longevity-focused daily routine for 2025, focusing on sleep, exercise, and eating well.

Search Result: NAD

Anti-Aging Supplement Rapamycin Increases Lean Mass and Reduces Pain: PEARL Trial Results

Jumpstarting the Brain Reduces Alzheimer’s Progression by 52% in New Phase II Trial.

Most Comprehensive Study Places NAD+ at Forefront of Countering Brain Aging

Weight Loss Drug Protects Against Diabetic Sarcopenia: New Study Finds

Longevity Fanatic Bryan Johnson’s Daily Aging Intervention Routine for 2025