What is NAD?

Researchers show that glyburide, an anti-diabetes drug, extends lifespan and reduces frailty in naturally aged mice.

Older adults with LDL cholesterol levels above 130 mg/dL live longer than older adults with LDL cholesterol levels below 130 mg/dL.

For the first time, a multi-nation panel of aging experts reached a consensus to designate markers of aging, which could make aging intervention testing easier.

Researchers found that alpha-ketoglutarate (αKG) can treat osteoarthritis by preserving cartilage and reducing joint inflammation.

Dr. Sinclair and collaborators show that an age-reversal technology that rejuvenates cells protects neurons from inflammation and cell death in mice.

The cutoff for vitamin B12 deficiency is too low, according to new findings showing that “normal” B12 levels are associated with neurological deficits in older adults.

The prescription drug rapamycin a.k.a. sirolimus, an FDA-approved mTOR inhibitor, increases the brain volume of cognitively normal individuals at risk for developing Alzheimer’s disease.

Dr. Aseem Malhotra, a cardiologist from the UK, says pharmaceutical company-sponsored research distorts the scientific evidence behind the effectiveness of cholesterol-lowering statins against heart disease.

While omega-3 supplementation slows biological aging, adding vitamin D and exercise further slows biological aging.

A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases.