What is NAD?

An extract made from Monarda didyma L. reduces the biological age of older adults while improving their quality of life.

A vaccine targeting an enzyme that breaks down NAD+, called CD38, counteracts signs of aging in mice.

The drug alfatradiol, also known as 17ɑ-estradiol, reduces cognitive errors on a test of memory and lowers neuronal plaques in mice genetically predisposed to Alzheimer’s disease.

Human studies show that a higher intake of the naturally occurring molecule spermidine may prevent cognitive impairments and dementia while improving longevity.

A 167-study analysis reveals that rapamycin prolongs lifespan as effectively as dietary restriction: reducing food intake without entering a state of malnourishment.

The diabetes drug canagliflozin improves learning and memory in middle-aged male mice and reduces brain plaques in Alzheimer’s model mice.

Plant-based molecule fisetin preserves muscle mass and strength in older mice via senolytic action — removal of senescent (dysfunctional) cells.

Researchers at the Max Planck Institute have unveiled that combining trametinib with rapamycin, drugs used in cancer treatment, extends average lifespan by 29% in female mice and 27% in male mice, respectively.

A new human study shows that a procedure involving the replacement of blood plasma with a fresh solution (therapeutic plasma exchange) lowers a measure of how quickly the body is aging (biological age).

Cornell and UPenn scientists find that mice introduced to the wild as infants age faster than lab mice, but what does this mean for humans?